Clario is the partner of choice for effective training.

In addition to eCOA device and systems user training, Clario offers training on how to complete clinical outcome assessments via our Rater Training and Participant & Caregiver Training solutions. This includes training on clinician reported- and patient reported- outcomes, and placebo response training.

Clario — one trusted source for all your training needs.

Our science-led approach to training improves clinical trial data quality and accuracy.

20+

years of eCOA experience

160k+

trained

33

indications

8

of top 10 biopharmaceutical companies

Why Clario’s Rater Training?

Reduce variability between raters

Clario’s Rater Training helps minimize errors, achieve high quality data, meet regulatory and industry recommendations, and improve clinical outcome assessment administration and scoring for your clinical trial.

Vast experience to support better outcomes

  • Built on 20+ years of eCOA expertise
  • 41K+ clinical site raters trained

Operational efficiency to reduce site burden

  • One system for training and eCOA
  • On-demand 24/7 access; accommodates rater turnover
  • Waiver system available for qualified raters
  • Standardized training available; certified raters don’t have to repeat training for a new study
  • Management of third-party training certifications

Training assurance for enhanced data quality

  • Rater qualification and certification
  • Gating to ensure only trained raters access eCOA
  • Ensures regulatory compliance; every training session is date- and time-stamped

Learn more about Rater Training with Clario

There is a strong relationship between inter-rater reliability and the number of participants needed to determine drug efficacy. Effective rater training can improve inter-rater reliability, reducing variability, and reduce the number of participants needed to power your clinical trial and the cost to bring your drug to market.1-3

Why Clario’s Participant and Caregiver Training?

Improve engagement and ensure consistency

Clario’s Participant & Caregiver Training is designed to help participants, caregivers, or both to better understand their roles and responsibilities in your clinical trial, which can improve compliance and engagement. It helps improve accurate reporting and reduce placebo effect, while establishing consistency throughout the study.

Vast experience to support better outcomes

  • Built on 20+ years of eCOA expertise
  • 125K+ participants and caregivers trained

Patient-centric approach to support reliable reporting

  • Multimedia training for engaging learning
  • Both training and eCOA is located on the same study device
  • Keeps key study details available for easy referencing at any time
  • Ensures that participants and caregivers understand how to complete assessments

Training assurance and compliance for enhanced data quality

  • Gating to ensure only trained participants and/or caregivers access eCOA
  • Ensures uniform training for all participants, across all sites
  • Safeguards regulatory compliance: every training session is date- and time-stamped

Learn more about Participant & Caregiver Training with Clario

Patient understanding of patient reported outcome (PRO) items was shown to increase with training, thus increasing the accuracy of data collected.4

Reduce placebo effect

Placebo effect results from a variety of causes, including patient-clinician interactions, patient expectations/beliefs, biases based on knowledge of drug/trial design, and familiarity with the patient. It’s most common in pain, migraine, itch, and gastrointestinal disorders, and can cause failure to determine treatment efficacy.

Clario’s Placebo Effect Training reduced placebo effect by more than 50% in a Phase III migraine study.5

Clario offers Placebo Effect Training for sites, participants, and caregivers.

Clario’s experience in numbers

41k+

clinical site raters trained

125k+

participants/caregivers trained

Therapeutic area training expertise

Plus other indications
  1. Sadler ME, et al. Int J Clin Trials. 2017;4(3): 101-10.
  2. Gwet KL. Handbook of inter-rater reliability, 4th edition; Maryland: Advanced Analytics, LLC; 2014.
  3. Leon AC. Schizophr Bull. 2008;34(4):664-9.
  4. Dias NR, et al. Patient Relat Outcome Meas. 2019 Nov 15;10:345.
  5. Macedo A., et al. Eur J Clin Pharmacol. 62, 161–172 (2006).