Cardiovascular & metabolic clinical trials

Advances in cardiac imaging give you an increasing number of modalities to choose from when planning a clinical trial. The choices can be overwhelming. But with Clario as a partner, you can be confident that your cardiac imaging needs are managed expertly — and within your budget.

When you partner with Clario for cardiac imaging and cardiac safety support, you begin an ongoing relationship with our multidisciplinary team. Combined with the industry’s most advanced technology, our cardiovascular and metabolic clinical trial management experts can help you plan a cardiovascular imaging and cardiac safety strategy specific to your needs:

  • Scientifically, you want to utilize modalities with the most sensitive and reliable data for your study
  • In terms of resources, you need a cardiovascular imaging protocol that takes into account the varied capabilities of diverse investigational sites as well as cardiac safety endpoints that will be required for regulatory submissions
  • From an enrollment standpoint, you want the safest and least invasive imaging and cardiac safety modalities for patients
  • Financially, you want an imaging and safety strategy that fits within your budget

Cardiovascular expertise


cardiovascular clinical trails


cardiovascular indications


non-cardiovascular endpoints


sites supported


Multidisciplinary team

We always include scientific experts in the discussion to make sure that your imaging and cardiac safety strategies will allow you to meet your milestones and match your resources. In the planning phase, our cardiovascular and metabolic clinical trial management teams work with scientific and regulatory experts to develop protocol alternatives that maintain your trial’s integrity while keeping budgetary and timeline concerns in mind.

Expert independent review

Our independent reviewers are experienced with the latest advances in evaluating cardiac structure and function as well as cardiac safety. Clario’s cardiovascular and metabolic clinical trial specialists analyze all images and other cardiac data from baseline through end-of-trial and support a wide range of imaging modalities.

Regulatory guidance

Clario’s experienced regulatory team participates in every step of the clinical trial process, providing expert guidance for submission to global regulatory agencies.


Our experience covers the complete range of modalities for cardiovascular research, including:

  • Angiography
    • Quantitative Coronary Angiography (QCA)
    • Quantitative Vascular Angiography (QVA)
  • Arrhythmia
    • Holter
    • Patch
  • Blood Pressure Services
    • ABPM
    • Clinic
    • Home
  • Electrocardiogram (ECG)
    • Clinic
    • Home
  • Computed Tomography Angiography (CTA)
  • Echocardiography
    • 2D/3D
    • M-Mode
    • Doppler
    • Tissue Doppler
    • Strain Imaging
  • Electronic Clinical Outcome Assessments (eCOA)
    • Patient Reported Outcomes (ePRO)
    • Clinician Reported Outcomes (eClinRO)
    • Observer Reported Outcomes (eObsRO)
    • Performance Outcomes (ePerfO)
  • Intravascular Ultrasound (IVUS) or US
  • Magnetic Resonance (MR)
    • Cardiac MR (CMR)
  • Nuclear Cardiology
    • Multiple Gated Acquisition (MUGA)
    • Positron Emission Tomography (PET)
    • Single Photon Emission Computed Tomography (SPECT)

Focus areas

Our experience in the cardiovascular clinical trial management area includes support for the following indications and areas:

  • Angina
  • Arrhythmias (supraventricular and ventricular)
  • Atherosclerosis/Coronary Artery Disease (CAD)
  • Cardiac Contrast Agents
  • Cardiac Tissue Ablation
  • Cardio-oncology
  • Cardiomyopathy
  • Congenital Channelopathies
  • Congenital Heart Disease
  • Congestive Heart Failure (CHF)
  • Deep Vein Thrombosis (DVT)
  • Duchenne’s Muscular Dystrophy
  • Fabry Disease
  • Giant Cell Arteritis
  • Hunter Syndrome
  • Hypertrophic Cardiomyopathy
  • Lipid disorders
  • Medical devices (including pacemakers, ICDs, coronary catheters, coronary stents and ablation catheters and mapping systems)
  • Myocardial Infarction (MI)
  • Myocardial Perfusion
  • Nonischemic Cardiomyopathies
  • Peripheral Vascular Disease (PVD)
  • Primary Hyperoxaluria
  • Pulmonary Hypertension
  • Sickle Cell Disease

Talk to a specialist

Our team of experts are available to address questions you may have about our cardiovascular and metabolic solutions. Submit your contact information and we’ll be in touch shortly.