900+
Studies supported
40+
Peer-reviewed manuscripts
170+
GLP-1 studies supported
Confidently accelerate your trials with accurate data at every phase
Stay on time and within budget with consistent, accurate endpoint data—partner with Clario for seamless support. Sponsors can confidently address critical trial endpoints by leveraging our innovative technologies including:
- Validated patient-centric tools
- Advanced imaging modalities
- AI-driven analytics
Click below to see a sample list of our capabilities for each of these critical trial endpoints:
Efficacy:
Accurately measure visceral and subcutaneous fat changes, as well as muscle mass changes, to demonstrate therapeutic benefits while characterizing potential risks.
Imaging assessments:
- DEXA for bone density and body composition analysis
- Liver fat imaging
- Cardiac imaging (echo and cMRI)
- Brain MRI (food-cue activation fMRI and volumetry)
Physical function tests:
- Activity tracking
- Gait analysis
- Standardized walk tests
- “Timed Up and Go” (TUG) test
Glucose monitoring:
- Integrated blood glucose monitor (BGM)
- Continuous glucose monitor (CGM)
Clinical endpoint adjudication
Safety:
Monitor and adjudicate hypoglycemia, suicidal ideation, and cardiovascular outcomes to meet safety and regulatory requirements. Study participants in this indication have elevated cardiovascular risk adding to study complexity.
- Electronic hypoglycemic event diaries
- Cardiac safety testing, including QT risk assessment with EPQT
- Clinical outcomes adjudication, including MACE events
- Blood pressure monitoring – intermittent home BP, clinic BP, or definitive ABPM studies
Patient Impact:
Differentiate therapies through Patient Reported Outcomes (PRO) data, including weight-related Quality of Life (QOL) and other validated measures that capture patient perspectives directly.
- Validated Quality of life and other health surveys
- Suicidality assessments with eC-SSRS
- Symptom diaries
Transform your clinical trials with our streamlined eCOA solutions
Ready to boost your study’s success? Read our case study to see how we accelerated a global Phase III weight management study.
Download case studyExperience in type 2 diabetes and obesity trials isn’t optional – it’s essential. Trust Clario.
Enhance the success of your type 2 diabetes and obesity clinical trials with Clario’s decades of expertise, providing precise measurement of efficacy, safety, and quality of life from start to finish. With a focus on delivering exceptional results, we offer:
Protocol design
Leverage our experience to design a robust study for precise execution and accurate results, giving you confidence in your trial’s foundation.
Endpoint expertise
Benefit from our scientists’ guidance in selecting optimal endpoint solutions for your goals, capturing reliable, high-quality data that drives meaningful insights for your development program.
Site management
Enjoy seamless operational support for every study location, regardless of scale or complexity, with our comprehensive global site support.
Patient support
Enhance the patient experience with our dedicated assistance, ensuring uninterrupted data collection and fostering positive trial outcomes.
Related resources
Optimizing Type 2 Diabetes and Obesity Trials
Integrating Diverse Endpoints to Holistically Assess GLP-1 Agonists and Beyond
Optimizing Obesity Trials: Integrating Diverse Endpoints to Holistically Assess Safety and Efficacy of GLP-1 Agonists and Beyond Webinar Replay
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