Dementias

Reveal deeper insights with advanced imaging

Neuroimaging is essential for tracking disease progression and treatment effect. Clario’s advanced MRI, CT, FDG-PET, and molecular imaging solutions provide precise, quantitative data to confirm eligibility, monitor change, and validate endpoints.

• Detect early structural and functional brain changes
• Visualize Tau and beta-amyloid with molecular imaging
• Standardize acquisition for consistent, reliable data
• Access expert reads aligned with regulatory criteria

Capture cognitive changes with smarter eCOA

Cognitive assessments are central to dementia trials – and precision is non-negotiable. Clario’s neuroscience-optimized eCOA platform ensures accuracy at every step, from rater training to data review.

• Deliver complex cognitive assessments with multimedia tools
• Equip raters with advanced, neuroscience-focused training
• Monitor in real time to detect and correct data quality issues
• Improve retention with eConsent and Patient Connect

Track subtle motor changes with wearable technology

Motor dysfunction often precedes cognitive symptoms in dementia. Clario’s Opal wearable sensors deliver objective, highly-sensitive data on gait and balance – capturing early signs of decline and enhancing your endpoint strategy.

• Detect early gait and balance impairments
• Collect real-world, continuous movement data
• Strengthen clinical outcome measures with objective insights

Watch our webinar on wearable sensor data.

Protect patient safety with integrated cardiac and respiratory monitoring

Older adults with dementia are at higher risk for cardiac and respiratory complications. Clario’s targeted safety solutions help you identify risks early and maintain compliance without slowing down your study.

• Monitor cardiovascular safety with intensive QT and BP assessments
• Capture high-quality spirometry and pulmonary function data
• Centralize safety oversight seamlessly across your study

Learn more about our cardiac and respiratory solutions.

Strengthen decisions with expert adjudication

In dementia trials, neuro-related events require precise evaluation to ensure consistent reporting. Clario’s Clinical Event Committee ensures accurate, defensible data to bolster your regulatory confidence.

• Centralize neuro-related event review with independent experts
• Standardized criteria for clear, defensible classifications
• Streamline regulatory submissions with high-quality data