Abstract Title: The use of wearable sensors and patient-reported outcomes in breast cancer research: A literature survey
Authors: Kelly Dumais, Adam Jagodinsky, Saima Khakwani, Rebecca Lydon, Bryan McDowell, Kristen Sowalsky
Session: Poster Session 5
Date: Friday December 8th, 2023
Time: 12:00 p.m. – 2:00 p.m. CST
Clinical outcome assessments (COAs) related to physical activity, sleep, and functional mobility (gait and balance) are common in breast cancer research as they provide insight into treatment effects and overall quality of life. Wearable sensors offer utility in supplementing traditional COAs by providing objective data by passive, continuous measurement, thereby gaining unique insight on functioning while reducing patient burden. However, a comprehensive understanding of how wearables are being used in breast cancer research and how they correlate with subjective measurement of functioning is lacking. We conducted a non-systematic survey of breast cancer literature using electronic databases (PubMed, Web of Science, Elsevier and Clinicaltrials.gov) to identify oncology trials using both wearable sensors and PROs. Sleep, quality of life, and physical activity were the most common outcomes measured by PROs, while physical activity and sleep were the most common outcomes captured using wearable sensors. The results suggest there is alignment in outcomes gathered from wearable sensors and PROs, however, additional insight may be gained by incorporating wearable sensors for assessment of functional mobility.
Director, eCOA Science and Consulting at Clario
Dr. Kelly Dumais is a scientist with over 13 years of experience in behavioral and life science research. She has expertise in the implementation of electronic clinical outcome assessments (eCOA) and the development and validation of patient-reported outcomes (PROs) to support labeling claims. She is currently the Director of eCOA Science and Consulting at Clario, a global data and technology company that helps to minimize risk in clinical trials. She consults on best practices for questionnaire design and eCOA design/use to drive data integrity and patient engagement and develops custom site rater training and participant training for improving accuracy in COA reporting and improving inter-and intra-rater reliability.
Principal Scientific Advisor, Clinical Science and Consulting, Precision Motion at Clario
Dr. Jagodinsky is a Principal Scientific Advisor and oncology lead on the Precision Motion Science and Consulting team where he works to advance the use of digital health technologies in clinical and academic research. Dr. Jagodinsky consults with sponsors on implementing wearable sensor solutions in clinical trials and provides comprehensive scientific support surrounding instrumented test and endpoint selection. Prior to joining Clario, Dr. Jagodinsky earned tenure in the Department of Exercise Science at Illinois State University. He has a background in biomechanics and human movement science, and his research focuses on the mechanics and control of gait and posture as well as leveraging technology for field-based human movement assessment.