ISCTM 22nd Annual Scientific Meeting
The ISCTM Annual Scientific Meeting is a premier conference organized by the International Society for CNS Clinical Trials and Methodology. It focuses on advancing the field of medical and pharmaceutical research, particularly in the area of central nervous system (CNS) clinical trials.
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Poster session information:
Date: Thursday, February 19, 2026
Time: 5:45 pm – 7:30 pm ET
Poster Session 1: Dr. Chris Brady – Population Norms of the tablet-administered Brief Assessment of Cognition
Abstract:
Understanding cognitive health is essential across many central nervous system conditions, and digital assessments can make this process faster and more reliable. In this study, researchers created population norms for the tablet based Brief Assessment of Cognition (BAC) using data from more than six hundred healthy adults who reflected United States demographic patterns. Participants completed six cognitive tests covering memory, working memory, motor function, verbal fluency, processing speed, and executive function. The team examined how age, sex, and education influenced performance. Age was strongly linked to lower scores on most tests. Women performed better than men on verbal memory, and individuals with higher education generally performed better across nearly all tests. These results allowed the researchers to generate standardized scores that can adjust for age, sex, and education when interpreting an individual’s cognitive performance. The findings provide an important resource for researchers and clinicians who use the tablet based BAC to detect and track cognitive changes across clinical populations.
Authors
- Chris Brady, Psy.D. – Vice President, Clinical Solutions at Clario
- Dorothee Schoemaker, Ph.Dl. – Senior Clinical Scientist at Clario
- Alexandria S. Atkins – Vice President of Scientific Development at VeraSci
- Matt Welch – Biostatistician at Clario
- Richard S.E. Keefe – Professor Emeritus at Duke University Medical Center
Research reported here was supported by the SBIC of the National Institutes of Health under award number 5R44AG053121-02.
Disclosures
DS, MW and CAB are full-time employees of Clario. Clario owns and distributes the paper BACS and the tablet administered BAC.
ASA contributed to the present work as a former full-time employee at VeraSci. She is currently a full-time employee and minor shareholder in Eli Lilly.
RSEK received consulting income from Boehringer Ingelheim, Damona Pharmaceuticals, Gedeon Richter, Kynexis, Merck, Neurocrine Biosciences, Inc., Novartis, Vandria, and WCG Clinical Endpoint Solutions; and received royalties from the BACS, SCoRS, and VRFCAT.
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