Session Information:
Session 1
Addressing Gaps in Inhalation QC in Forced Spirometry Maneuvers
PS-14 / Session 43 / PA398
Date: Sunday, September 28, 2025
Time: 8:00 – 9:30 CET
Clario authors:
- Paul Desbordes, Ph.D. – Team Lead, R&D Software Engineering, AI
- Kevin McCarthy, RPFT, ATSF – Senior Director, Scientific Affairs, Respiratory
- Todd Lustine M.D., MS, FCCP – VP, Medical Science, Respiratory
- Carl Mottram – Senior Scientific Advisor, Respiratory
- Marko Topalovic, Ph.D. – SVP, Chief AI Officer
Session 2
Comparison of the FEV1/FVC lower limit of normal and a fixed threshold of 0.70 for ruling out significant airway obstruction in clinical trials for IPF
PS-25 / Session 55 / PA636
Date: Sunday, September 28, 2025
Time: 8:00 – 9:30 CET
Clario authors:
- Kevin McCarthy, RPFT, ATSF – Senior Director, Scientific Affairs, Respiratory
- Phil Lake, Ph.D. – Senior Director, Respiratory Solutions
- Todd Lustine M.D., MS, FCCP – VP, Medical Science, Respiratory
- Carl Mottram – Senior Scientific Advisor, Respiratory
Session 3
Artificial intelligence (AI) software for spirometry quality control: external validation in primary care
PS-3 / Session 238 / PA2884
Date: Monday, September 29, 2025
Time: 8:00 – 9:30 CET
Clario authors:
- Karolien Van Orshoven, MSc – Program Manager
- Maarten de Vos, Ph.D. – R&D Advisor, AI
- Paul Desbordes, Ph.D. – Team Lead, R&D Software Engineering, AI
- David Scott, Ph.D. – VP, Medical & Scientific Affairs, Neuro & CVI
- Marko Topalovic, Ph.D. – SVP, Chief AI Officer
Additional authors from:
UNSW Sydney, Harefield Respiratory Research Group, Cambridge University Hospitals NHS Foundation Trust, George Eliot Hospital NHS Trust, University Hospitals Coventry and Warwickshire NHS Trust, University of Leicester, Wolfson Palliative Care Research Centre, Kings College London, NHS South England, Asthma + Lung UK, Imperial College London, Queen Mary University, and University of Southampton
Session 4
Experience in a clinical trial for COPD suggests the reduced back-extrapolated volume limit of 0.100 L is unnecessarily restrictive
PS-27 / Session 495 / PA5954
Date: Tuesday, September 30, 2025
Time: 12:30 – 14:00 CET
Clario authors:
- Kevin McCarthy, RPFT, ATSF – Senior Director, Scientific Affairs, Respiratory
- Phil Lake, Ph.D. – Senior Director, Respiratory Solutions
- Todd Lustine M.D., MS, FCCP – VP, Medical Science, Respiratory
- Carl Mottram – Senior Scientific Advisor, Respiratory
Session 5
The prevalence of submaximal effort on the reported FEV1 in a clinical trial cohort of Asthma, COPD, and ACO subjects
PS-27 / Session 495 / PA5953
Date: Tuesday, September 30, 2025
Time: 12:30 – 14:00 CET
Clario authors:
- Carl Mottram – Senior Scientific Advisor, Respiratory
- Paul Desbordes, Ph.D. – Team Lead, R&D Software Engineering, AI
- Todd Lustine M.D., MS, FCCP – VP, Medical Science, Respiratory
- Kevin McCarthy, RPFT, ATSF – Senior Director, Scientific Affairs, Respiratory
- Marko Topalovic, Ph.D. – SVP, Chief AI Officer
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