Poster title: The Potential for Baseline Spirometry Variability to Generate Increased Treatment Response in IPF
Date: Sunday, August 21, 2024
Time: 3:15 p.m. ET
Abstract:
We have noted an unexpectedly high incidence of IPF patients who appear to show increased FVC values over relatively short intervals within clinical trials. Given the progressive nature of the underlying disease and the limited potential for structural change over a matter of weeks we decided to explore this effect to see if this was related to spirometry technique or a learning effect could explain this phenomena.
Join this poster session to learn more about our methods and results from this research.
Senior Director, Respiratory Solutions at Clario
Phil Lake is a respiratory specialist at Clario who supports global clients. He has held various roles in drug development for 20 years, predominantly focused on respiratory trials. Prior to Clario, Phil worked on several anti-inflammatory agents, dual and triple combination therapy, monoclonal antibody studies, anti-infectives and some of the largest mechanistic studies looking at biomarkers within sputum and biopsy samples at SmithKline Beecham and GlaxoSmithKline. He has experience supporting CROs as a respiratory specialist and as the head of project management. Recently, his concentration has been extensively on rare respiratory diseases, including Cystic Fibrosis and Idiopathic Pulmonary Fibrosis, covering a variety of drug mechanisms and medical devices. Phil was pivotal to some of the first centralized overread studies and is committed to driving improvements in lung function testing.