Phase II/III experience data
17,000+
clinical trials supported
85,000+
trial sites enabled
6,200,000+
participants engaged
Proven solutions to reduce variability and strengthen data reliability
In Phase II and III trials, data integrity and consistency are paramount. Our technology and scientific experts ensure your endpoints are measured with the same rigor and precision across every site, country, and patient population. We help you reduce variability, optimize data quality, and confidently meet global regulatory standards.
Clario supports your late phase studies with proven, scalable solutions:
Imaging solutions
Deliver consistent, high-quality imaging data across every site. Clario’s centralized services combine standardized protocols, AI-enhanced reads, and expert oversight to reduce variability and boost reliability.
Our global infrastructure scales to any trial size with rapid site onboarding and seamless image management – accelerating timelines while providing regulatory confidence.
eCOA solutions
We work with a network of pre-screened, highly trained Phase I sites across the globe to collect reproducible, high-quality digital ECG data. These sites are continually evaluated to ensure they meet data quality standards.
Additionally, by working with well-trained and well-equipped sites, you will increase the potential to reduce study start-up time.
Cardiac solutions
Monitor cardiac endpoints for safety and efficacy with precision. Clario delivers gold-standard ECG and spirometry data through advanced technologies, centralized expert review, and globally consistent workflows.
Our solutions support confident safety and efficacy evaluations and help you meet ICH E14 and other regulatory requirements across all trial phases.
Respiratory solutions
Standardize pulmonary endpoints whether in respiratory trials or assessing toxicity in non-respiratory development programs.
Clario’s respiratory solutions provide high-quality, reproducible spirometry and lung function data through centralized oversight, standardized protocols, and technician training. Built-in quality control and expert review promises every data point strengthens decision-making and regulatory submissions.
Clinical adjudication
Simplify clinical event adjudication and reduce trial delays. Clario offers comprehensive clinical adjudication services through a secure, centralized platform that streamlines case submission, committee review, and documentation.
Our team supports you with best-practice workflows, experienced clinical experts, and audit-ready reporting. This helps you reduce delays, improve data integrity, and deliver confidently to regulators.
Digital movement analysis
Gain real-world functional insights with validated wearable technology.
Clario’s Digital Movement Analysis, powered by the Opal V2C® wearable sensor system, delivers precise, real-world assessments of gait, balance, and mobility. Lightweight and easy to use in both clinic and home settings, Opal V2C enables continuous data collection and deeper insights into treatment impact while reducing burden on patients and sites.
Drive better outcomes with scientifically-driven trial design
Align your endpoints with the evidence regulators expect
Successful Phase II and III trials start with defining the right strategy. Our scientists and medical experts collaborate with your team to select clinical endpoints that matter – aligning with regulatory guidance and delivering measurable, meaningful results. From adaptive designs to complex multi-modality assessments, we help you build a smarter trial from the start.
Clario offers expert scientific consulting and execution including:
- Crafting endpoint strategies that drive approvals
- Optimizing protocols for feasibility and efficiency
- Guiding regulatory alignment and readiness
- Streamlining operational planning across all modalities
